SmartBackup looks like a good app to me however I haven't used it myself.
http://freeridecoding.com/smartbackup/
If you want online backup, check out mozy.com, you get 2GB free space which you can use for more important files. I'm using the unlimited paid version myself and have 80GB stored online.
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MacBook Pro 2.16GHz Core2Duo 3GB RAM, G4 1.4GHz OSX Tiger 1.25GB RAM, Dual 2GHz G5 OSX Tiger 2GB RAM (freakin shweet)
Athlon 64 Windoze XP for school work (programming) 1GB RAM
dferns@macosx.com