You should check out Syncronize Pro from
Qdea. It has a truckload of options when you really want to tap into its potential, yet is so easy to set up for automatic syncronizations and backups that its plain silly. I use it all the time for both bootable backups, partial backups, backups over SMB (my network shares to a fw backup drive), syncronization between USB thumdrives/pendrives and my laptop disk and so forth... Also, they have excellent customer support.
Yes, its shareware, but worth its price in full.
