Bill have you got this working yet, I have the same problem.I just bought a small scanner - an Epson Perfection 3490 Photo and cannot get the Driver to work with it. I run OSx 10.4.7 on a laptop powerbook and installed the software from the disc supplier with the unit. Nothing worked so I went on line and dowloaded the reccomended driver from Epson and it refused to work as well. After contacting Epson I got their regular list of "Uninstall all these files...." and then restart and re-install the software. I have done all this several times and still it will not work (at all). All that happens when I double click on the Scanner driver is that it temporarily pops up in the Dock and as soon as I click on my scanner model in the drop down window the icon in the dock dissapears.
Can anyone offer some assistance?