Since updated to OS 10.2.2 Control-Option-Esc no longer functions as a force quit, no longer functions at all. If anyone has any feedback it'd be much appreciated.
Somewhere else on this board it was stated that the window may just be stuck behind another window ... after pressing command-option-esc try hitting the return key. Force Quit normally selects which program is hanging and its more than likley that your culpret will be selected when you hit return.