There were releases of both Prince of Persia 1 & 2 for Mac; it's also one of the first games I ever owned. As for my favs, here they are, going backwards in time:
Ghost Recon
Jedi Knight II: Jedi Outcast
Fallout 2
Medal of Honor: Allied Assault
Return to Castle Wolfenstein (playing the Time Gate conversion right now, pretty good)
Baldur's Gate 2
Quake 3 (ridiculously addictive, totally mindless)
Baldur's Gate
Diablo 2 & LOD (great game)
Unreal Tournament
Quake 2
Myth 2: Soulblighter (now playing the OS X version, quite nice)
Myth: The Fallen Lords
Quake
Escape Velocty, EV: Override, & EV: Nova (still playing)
Fallout
Marathon Infinity
Marathon 2: Durandal
Marathon
Prince of Persia 1 & 2
NES, SNES, GameBoy