This would be a VERY bad idea. Mac OS X, like all Unix based systems, relies on a few particular folders being where they are expected to be. This includes not only /Users, but a lot of the hidden folders you never see.
Removing the Users folder, though it is possible, would almost certainly disrupt software installs, opening documents, logging on, and just about ANYTHING. This is why it is set with such tight permissions that you'd need to sudo to remove it. Don't do it!
Instead, why not look at other approaches to the problem. What is it Suitcase 11 actually needs? Can this be achieved by just making a new folder as a storage spot for fonts? Or setting up an alias to your ~/Library/Fonts file?
LUCKY 2000th POST!