the first version ever of flight simulator by microsoft was made exclusively for the macintosh. I remember many hours playing it on my Mac SE. It was on one floppy disk that the computer started off (startup disk). You could fly about 3 planes and fly between airports and could even do world war 2 missions with bombs and dogfights. Excellent fun on a black and white screen. (not grey scale from memory).
sorry no, i dont have a clue if they still make a Mac OS X compatible version