Sure - if you can't afford enough space. You still pay a good premium to get a lot of space on an SSD. In my experience, the files that you mention don't usually take up a significant amount of space, and you may get up to 5 GB from that process (assuming that your Mac system is functioning properly), but not every time that you clean. If that small amount makes a big difference for you, then you need to consider external storage, in addition to your internal boot drive.