I have the CanoScan N1220U. I love the scanner, but it doesn't sem to be supported by OS X. The main way I import is through PhotoShop (the light version conveniently came with the scanner), which is not an OS X app. There is also a 'scanner toolbar' which pops up when the button on the scanner is pressed. That's not an OS X app either.
So unless there is some configuration thing that I am missing, the N1220U isn't compatible with OS X. Maybe PhotoShop for OS X will import properly...