Run 2 mice / 2 pointers at the same time on OS X?

You can run as many as you want. I run an external trackpad and a mouse now but I've had multiple mice connected as well as multiple keyboards.

They're just another USB (or Bluetooth) device to OSX.
 
Doesn't look like that's going to happen on Mac OS X right now.

In addition, the Microsoft multipoint you linked to isn't exactly what you're describing -- it doesn't let any application have multiple, independent cursors sending input to a program... programs have to be specially written (via APIs) in order to take advantage of Microsoft multipoint. As of now, not many popular, 3rd-party applications do this.
 
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