Safari Fails to Open


I downloaded the latest security updates for my MAC OSX (I cannot remember what particular update it was) and after my laptop had rebooted, Safari (along with LimeWire and Acquisition) wouldn't work. It wouldn't even open. I'd click the Safari icon in the dock and it'd bounce once and then nothing would happen. I tried downloading Safari 1.2 again, but still it wouldn't work. I don't know what to do and I would really like to be able to use Safari again (along with those other programmes). Help? Please? Anyone?
First, check all the additional plug-ins you have added to Safari (~/Library/Application\ Support/SIMBL/Plugins). Also try Repairing Permissions with Disk Utility (/Applications/Utilities/Disk Utility). Good Luck.
I am having the same problem. I ran the OS update, but it failed to run every time I tried it. Now Safari will not work at all. I tried repairing permissions, but that didn't help either.